Manufactorum

Through the strange, transparent shield could dozens of Saeva Simius, being restrained by machinery as it worked over them, injecting them with a strange variety of drugs. Their heads were encased in small metal domes for memory replacement and loyalty enhancements. All appeared to be in the final stages of production. A Synth Soldier was patrolling the room with his Plasma Rifle in hand, examining the monitors as he went. The Civilis Protectione Ground Unit from earlier entered, but he was different now. He stumbled slightly, clearly not used to his increased height and augments. He stumbled over to the free device on the far end of the room, and turned with a grunt. Two metallic arms came down and lifted him from the ground, raising him into the air slightly as the metal casing clasped around his head, cutting him off from the room. The Synth Soldier went over and tapped a few commands into the terminal, waving his hand over the biolock to activate it and then turning, returning to his patrol.
There was a clunk as the bulkhead behind them snapped open to reveal a room with multiple Saeva Simius lying on metal slabs with machinery working on them. A Synth Soldier walked among them, checking the machinery was functioning correcting and checking their vital signs, administering medical attention as required to ensure the subjects didn't expire. The majority of Saeva Simius here were actually volunteer's, as was apparent by the way the majority just submitted to the treatment. There were a few who weren't, but the sad truth was the Saeva Simius just wanted war.
Overhead was a seemingly endless system of pod transports with a variety of subjects inside, clunking over head as they moved to their destinations, the roof far above. Scanners flew around the pods, scanning them and checking their subjects. There was another announcement, and then large platform moved over. Inside could be seen stacks of dead bodies on their way to recycling. There was a set of pods flying over as an Umbrae Populus shouted, demanding to be released as the system processed him and decided his destination. [img=http://static3.wikia.nocookie.net/__cb20090804105647/half-life/en/images/7/75/D3_citadel_020024.JPG]

Regardless of whether the majority of this worlds subjects were volunteers or not, they were clearly worked on while they were awake, the Collective either unwilling to knock them out or unable to do it on such a large scale to knock out the tens, maybe hundreds of thousands the facility was working on