You looking at like alien proliferation or mostly humans?
One big government like The Empire/Star Trek thing or several smaller ones?
What sort of tech?
Like sort of low future, just get into FTL, pistols and shotguns but also laser variants and jet packs.  Or are regular kinetic weapons basically obsolete.  Any sort of retro vibe with the cyberpunk...like The Future as imagined in the 60s/80s or just straight like modern concept futuristic?

It's a fun idea.