[quote=@Sep]
<Snipped quote by Cyrania>

Totally unique idea, never done before. What if Iris was the Flash? 🤔
[/quote]

That could be interesting. 

Barry could be her science guy and contact with the police force. She could be using her new speed powers for her journalism.

Reverse Flash and Professor Zoom could become women, or you would have some very interesting character dynamic differences where one or both of them remain men.