[quote=@Etcetera]
<Snipped quote by Tank O The Lake>

I can't say I'm familiar, but a technoboost qualifies as far as I'm concerned.
[/quote]

Yeah, the hunters are, for the most part, kind of just people.  They're extremely skilled people, sure, but they don't have much other than skill, mettle, and technology/magic to fall back on, whereas Lucy has near-godlike intrinsic power.  It makes the fight inherently an uphill battle.