I don't have anything for the sedatives Rex :P
Wasn't really that important, maybe like the mother was a pharmacist or something but having Angel and Ash as acquaintances sounds good. Maybe Ash gets all defensive when Angel tries anything on Sloth xD. I think my relationship with Gluttony will be one where Ash is extremely weary of him and always watching him due to his 'air of superiority' thus he is always watching him to see whether he'll cross the line, can relate to Wrath in a sense that they both seem to have bad times with their parents (right? :d ) and with Pride is where his curiosity somewhat lies, although he doesn't pry too much.