Ai-chan
- OC × Kizuna Ai+
Akame ga Kill!
- Alternate timeline
-- OC × Chelsea
And You Thought There is Never a Girl Online?
- OC × Akane Segawa/Schwein (this one is SPECIFICALLY F×F/yuri)
- OC × Nanako Akiyama/Sette
Angel Beats!
- The New Angel+
- OC × Yuri Nakamura (alternate timeline)
- OC × Eri Shiina
- OC × Yusa
- OC × Yui (alternate timeline)
- OC × Hisako
- OC × Masami Iwasawa
- OC × Miyuki Irie
- OC × Shiori Sekine
- OC × OC
Ayakashiko
- OC × Mahoro Miyatsuka
Black★Rock Shooter
- OC × Rock (B★RS: Innocent Soul)
- OC × Stella (B★RS: The Game manga)
Cage of Eden
- OC × Mami Kagura
- OC × Yuki Sakuma
- OC × Maya Miyauchi
- OC × Shizuka Hatsuse
- OC × Aya Tokiwa
- Las Cinco Muertes (Jurassic Park crossover) +
A Centaur's Life
- OC × OC
- OC × Nozomi Gokuraku
A Certain Scientific Railgun*
- OC (Ryūji Minamoto) × Mikoto Misaka
- OC (Ryūko Minamoto; Ryūji genderbend) × Mikoto Misaka
- OC (Ryūji/Ryūko) × Ruiko Saten
Crush Crush
- OC × Cassie
- OC × Iro
- OC × Fumi
- OC × Alpha
- OC × Pamu
- OC × Eva
The Devil is a Part-Timer! (includes the "Highschool!" spinoff)
- OC × Emi Yusa
- OC × Suzuno Kamazuki
- OC × Emeralda Etuva
Digimon
- OC (Rex Drake) × Zoe Orimoto/Rika Nonaka/Nene Amano
Expelled From Paradise
- OC × Angela Balzac +
Gargantia on the Verdurous Planet
- OC × Amy (alternate timeline)
- OC × Bellows
- OC × Melty
- OC × Ridget
- OC × Saaya
Highschool of the Dead*
- OC (Mason Crosby) × Saeko Busujima
ID-O
- OC × Maya Mikuri
- OC × Clair Hojo
Interviews With Monster Girls*
- OC × OC
- OC × Hikari Takanashi +
- OC × Himari Takanashi +
- OC × Yuki Kusakabe
Is This a Zombie?
- Is This a Dragon? (OC × Taeko Hiramatsu or Kanami Mihara) +
- OC × Kyoko
Miss Kobayashi's Dragon Maid*
- OC human × OC dragon +
- OC dragon × bandit girl +
Monster Hunter
- 4th Gen (Monster Hunter 4 Ultimate or Generations-based)
- Monster Hunter Stories-based (also Monster Hunter Stories: Ride On)
Monster Musume*
- OC × OC
- OC × Luz Ninetei
- OC × Kyuri Drakulya
- Everyday Life in Witness Protection +
Pokémon
- OC (Rex Drake) × Serena (anime) +
- OC × May (ORAS)
- OC × Shauna (XY)
- OC × Emma (XY)
- OC × Lisia (ORAS)
- OC × Lillie (SM) +
- OC × Furisode Girl(s) +
RWBY*
- OC (Jett Ryu) x Ruby Rose +
- OC (Kanzo Ryu; Jett genderbend) × Ruby Rose +
- OC (Gray Halseyon) x Weiss Schnee
- OC (Ash Halseyon; Gray genderbend) × Weiss Schnee
- OC (Gray Halseyon) x Cinder Fall
- OC (Ash Halseyon) × Cinder Fall
- OC (Gray Halseyon) × Neopolitan
- OC (Ash Halseyon) × Neopolitan
- OC (Amarok Paladus) x Blake Belladonna
- OC (Argent Paladus; Amarok genderbend) × Blake Belladonna
- OC (Amarok Paladus) x Yang Xiao Long
- OC (Argent Paladus) × Yang Xiao Long
- OC (Amarok Paladus) x Velvet Scarletina +
- OC (Argent Paladus) × Velvet Scarletina +
- OC (Stone Ryu) × Glynda Goodwitch (younger)
- The Crystal Ball + (post-apocalyptic AU)
Soul Eater & Soul Eater NOT
- OC × OC
- OC × Maka Albarn
- OC × Tsubaki Nakatsukasa
- OC × Tsugumi Harudori
- OC × Kim Diehl
Upotte!!
- OC (Mk.14 EBR, aka Maku) × Ichiroku
- OC (Ryūji/Ryūko Howa) × Ichiroku
- OC (Anaguma, AKA Honey Badger) × Ichiroku
- OC (Mk.14 EBR) × Sig
- OC (Ryūji/Ryūko) × Sig
- OC (Anaguma) × Sig
- OC (Mk.14) × Saiga
- OC (Ryūji/Ryūko) × Saiga
- OC (Anaguma) × Saiga
Vocaloid
- OC manager/security × Hatsune Miku (preferably 'World is Mine' version)
- OC manager/security × Megurine Luka
- Love triangle of the above pairings
- OC × SF-A2 Miki
- OC × Yuzuki Yukari
- OC × Anon and/or Kanon
- OC × Gumi
- OC × Lily
- OC × Kokone
- OC × IA
- OC × Anri Rune
- OC × Yowane Haku
Yandere Simulator
- Mysteries of Akademi + _{(very much OC × Oka Ruto, but Oka is a secondary main character; think Minori Kushieda in Toradora!)}
Z-Girls _(game)
- OC × Saki
- OC × Fudo
- OC × Masami
- OC × Chika
- OC × Kirine *******
- OC × Hiyori
- OC × Izumi

Almost any of these can be combined in some way, shape or form; anything italicized is the role I prefer
- Vampire master/mistress×human servant
- Human×guardian angel/spirit
- Anything with dragons
- Anything with dinosaurs
- Human×kemonomimi (leaning towards neko and kitsune)*
- Teenage Wasteland
- Young man×tsundere/himedere
- A Gentleman in the Apocalypse
- Cryptid/monster hunters
- Brother/Step brother/half brother×sister/step sister/half sister
- Human×monster girl (inspired by Monster Girl Encyclopedia and Monster Musume; please ask about my preferences on the monster girls)
- Slacker×highschool student president/disciplinary committee member
- Childhood friends
- Heiress×servant/bodyguard
- Senpai×kōhai
- Accel World/SAO-inspired setting (but not in either series)