@ZarkunAlso, in the case of the 3 God Slayers we have(Argus, Nolan, and Jack), wouldn't she be at a disadvantage, since her magic is divine/holy?
Does god slayer magic have an advantage over holy magic? because her magic originates from an angel, not a god directly. However angels do work for gods so unsure.
I also didn't think god slayers had an advantage over holy magic to be honest

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I honestly couldn't say. Jack's magic is a generational thing, Nolan learned his from a bunch of pacifist monks and Argus is...Argus XD Probably the only one who'd feel a need to fight her right away.
Honestly Jack would destroy her and it would be amusing

However Nolan uses ash doesn't he? What would happen if that got wet? And unsure how she would cope with Argus to be honest XD
Overall I would assume some kind of angel slayer would be most effective against Manami's magic.